STRICT REQUIREMENT: You must be in contact with our Doctor on duty before proceeding with this medication.
Mifepristone: Mechanism & Uses
| Feature | Description |
|---|---|
| Drug Class | Antiprogestin (Progesterone receptor antagonist) |
| Mechanism | Blocks progesterone. This hormone is essential for pregnancy maintenance. Blocking it causes the uterine lining to break down and softens the cervix. |
| Primary Uses |
1. Medical termination of pregnancy (combined with Misoprostol). 2. Management of hyperglycemia in Cushing’s syndrome. |
| Contraindications | Ectopic pregnancy, chronic adrenal failure, hemorrhagic disorders, or concurrent anticoagulant therapy. |
Misoprostol (Cytotec®)
| Feature | Description |
|---|---|
| Drug Class | Synthetic Prostaglandin E1 analog |
| Mechanism | Induces contractions. Binds to uterine receptors to cause strong contractions and cervical ripening (dilation). |
| Uses |
1. Prevention of NSAID-induced ulcers. 2. Off-label: Medical abortion, miscarriage management, labor induction. |
| Side Effects | Diarrhea, strong abdominal cramping, nausea, chills (transient fever). |
Combined Protocol
| Feature | Mifepristone | Misoprostol |
|---|---|---|
| Role | The Blocker: Stops pregnancy growth. | The Expeller: Empties the uterus. |
| Typical Dose | 200 mg (1 tablet) orally. | 800 mcg (4 tablets) taken 24–48 hours later. |
| Efficacy | The combined regimen is 95-98% effective for early gestation. | |
Avoid Counterfeit Medication
Counterfeit pills are common online. They may be ineffective or contain dangerous ingredients.
- Verify the Source: Authentic medication requires a provider consultation.
- Check the Product: Genuine Cytotec® is white, hexagonal, engraved with “SEARLE” or “1461”.
- Inspect Packaging: Look for professional blister packs with batch numbers.
If you suspect fakes, contact a healthcare professional immediately.
Medically Reviewed By:
Dr. Bolanle Aina, Pharmacist
(Aug 2023)

